Endocrine Abstracts

Progesterone (PRG) deficiency has been linked to an increased risk of cancer, while normal levels of PRG in the body actually help protect you against some forms of cancer. The tumor suppressor role of this steroid was envisaged, however the mechanism through which this occurs was not clearly established. The effects of progesterone act via the progesterone receptor (PR) of which two isoforms, called A (PR-A) and B (PR-B) were discovered. Herein, we present a novel finding sin...